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Meningioma epigenetic grouping reveals biologic drivers and therapeutic vulnerabilities

2020-11-27

Abstract excerpt

<h4>SUMMARY</h4> Meningiomas arising from the meningothelial central nervous system lining are the most common primary intracranial tumors, and a significant cause of neurologic morbidity and mortality 1 . There are no effective medical therapies for meningioma patients 2,3 , and new treatments have been encumbered by limited understanding of meningioma biology. DNA methylation profiling provides robust classifica...

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Literature Corpus work
a8d8c74f-e9a6-5816-b5e1-c82cdd8c17bb
DOI
10.1101/2020.11.23.20237495
Open publication

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Meningioma epigenetic grouping reveals biologic drivers and therapeutic vulnerabilitiesDOI 10.1101/2020.11.23.20237495
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