Article
A Tail Fiber Engineering Platform for Improved Bacterial Transduction-Based Diagnostic Reagents.
ACS synthetic biology - 18 Jun 2021
Lam Colin N, Mehta-Kolte Misha G, Martins-Sorenson Natacha, Eckert Barbara, Lin Patrick H, Chu Kristina, Moghaddasi Arrash, Goldman Dylan, Nguyen Hai, Chan Ryan, Nukala Laxmi, Suko Shawn, Hanson Brett, Yuan Richard, Cady Kyle C
Abstract excerpt
Bacterial transduction particles were critical to early advances in molecular biology and are currently experiencing a resurgence in interest within the diagnostic and therapeutic fields. The difficulty of developing a robust and specific transduction reagent capable of delivering a genetic payload to the diversity of strains constituting a given bacterial species or genus is a major impediment to their expanded...
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