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SpyPhage: A Cell-Free TXTL Platform for Rapid Engineering of Targeted Phage Therapies

4 Oct 2022

Abstract excerpt

The past decade has seen the emergence of multidrug resistant pathogens as a leading cause of death worldwide, reigniting interest in the field of phage therapy. Modern advances in the genetic engineering of bacteriophages have enabled several useful results including host range alterations, constitutive lytic growth, and control over phage replication. However, the slow licensing process of genetically modified...

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PMID: 36194543
DOI: 10.1021/acssynbio.2c00244

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