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HLA Diversity in Saudi Population: High Frequency of Homozygous HLA Alleles and Haplotypes

9 Jun 2022

Abstract excerpt

Human leukocyte antigens (HLA) diversity has a tremendous impact on shaping the transplantation practices, transfusion-associated graft versus host disease prevention strategies, and host–pathogen interactions. Here, we conducted a retrospective study of HLA class I and class II homozygosity at allelic and haplotype levels in unrelated individuals genotyped from 2012 to 2016 in a tertiary hospital in the capital...

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PMID: 35754807
DOI: 10.3389/fgene.2022.898235

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