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Article

Distinct mutational backgrounds and clonal architectures implicated prognostic discrepancies in small-cell carcinomas of the esophagus and lung.

Cell death & disease - 12 May 2021

Song Zhengbo, Liu Yueping, Cheng Guoping, Chang Lianpeng, Yu Zicheng, Chen Ming, Chen Gang

Abstract excerpt

Small-cell carcinoma of the esophagus (SCCE) is a rare and aggressive cancer. Although several consistent genomic changes were observed previously between SCCE and small-cell lung cancer (SCLC), detailed mutational landscapes revealing discrepancies in genetic underpinnings of tumorigenesis between these two cancers are scarce, and little attention has been paid to answer whether these genetic alterations were...

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Identifiers

PMID: 33980813
DOI: 10.1038/s41419-021-03754-0
PMCID: PMC8115141

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