Article
Nuclear YB-1 expression as a negative prognostic marker in nonsmall cell lung cancer.
The European respiratory journal - 1 Jan 2004
Gessner C, Woischwill C, Schumacher A, Liebers U, Kuhn H, Stiehl P, Jürchott K, Royer H D, Witt C, Wolff G
Abstract excerpt
The human Y-box binding protein, YB-1, is a multifunctional protein that regulates gene expression. Nuclear expression of YB-1 has been associated with chemoresistance and poor prognosis of tumour patients. Representative samples from autopsied material of primary tumours from 77 patients with NS...
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