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Article

Tumor Mutation Burden and Immune Invasion Characteristics in Triple Negative Breast Cancer: Genome High-Throughput Data Analysis.

Frontiers in immunology - 1 Jan 2021

Gao Chundi, Li Huayao, Liu Cun, Xu Xiaowei, Zhuang Jing, Zhou Chao, Liu Lijuan, Feng Fubin, Sun Changgang

Abstract excerpt

In recent years, the emergence of immunotherapy has provided a new perspective for the treatment and management of triple-negative breast cancer (TNBC). However, the relationship between tumor mutation burden (TMB) and immune infiltration and the prognosis of TNBC remains unclear. In this study, to explore the immunogenicity of TNBC, we divided patients with TNBC into high and low TMB groups based on the somatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33968045
DOI: 10.3389/fimmu.2021.650491
PMCID: PMC8097167

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