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Article

Integrating Genomic Information with Tumor-Immune Microenvironment in Triple-Negative Breast Cancer.

International journal of environmental research and public health - 26 Oct 2022

Otohinoyi David, Kuchi Aditi, Wu Jiande, Hicks Chindo

Abstract excerpt

BACKGROUND: the development and progression of triple-negative breast cancer (TNBC) is driven by somatic driver mutations and the tumor-immune microenvironment. To date, data on somatic mutations has not been leveraged and integrated with information on the immune microenvironment to elucidate the possible oncogenic interactions and their potential effects on clinical outcomes. Here, we investigated possible...

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Identifiers

PMID: 36360779
DOI: 10.3390/ijerph192113901
PMCID: PMC9659069

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