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Identification of an immune cell infiltration-related gene signature for prognosis prediction in triple-negative breast cancer.

Cellular and molecular biology (Noisy-le-Grand, France) - 8 Oct 2024

Wang Yan, Zhang Nianqing, Zhang Bo, Chen Yong

Abstract excerpt

Triple-negative breast cancer TNBC with higher immunogenicity and tumor-infiltrating lymphocyte (TIL) enrichment can benefit from immunotherapy relative to other breast cancer subtypes. Our work was designed to identify the TIL-related hub genes in TNBC and construct a prognostic signature for TNBC. TNBC gene expression files were obtained from the TCGA database. CIBERSORT algorithm and random forest risk model...

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PMID: 39380273
DOI: 10.14715/cmb/2024.70.9.13

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