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Article

PEG3 mutation is associated with elevated tumor mutation burden and poor prognosis in breast cancer.

Bioscience reports - 28 Aug 2020

Zhang Min, Zhang Jin

Abstract excerpt

BACKGROUND: Breast cancer is the second most common malignancy in women and considered as a severe health burden. PEG3 mutations have been observed in several cancers. However, the associations of PEG3 mutation with tumor mutation burden (TMB) and prognosis in breast cancer have not been investigated. METHODS: In our study, the somatic mutation data of 986 breast cancer patients from The Cancer Genome Atlas...

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Identifiers

PMID: 32729618
DOI: 10.1042/BSR20201648
PMCID: PMC7419805

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