Article
RAS-Mutant Follicular Thyroid Tumors: A Continuous Challenge for Pathologists.
Endocrine pathology - 1 Sept 2024
Hernandez-Prera Juan C, Wenig Bruce M
Abstract excerpt
The classification of thyroid nodules, particularly those with a follicular growth pattern, has significantly evolved. These tumors, enriched with RAS or RAS-like mutations, remain challenging for pathologists due to variables such as nuclear atypia, invasion, mitotic activity, and tumor necrosis. This review addresses the histological correlates of benign, low-risk, and malignant RAS-mutant thyroid tumors, as...
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