Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of RAS p.Q61R by Immunohistochemistry in Practice: A Clinicopathologic Study of 217 Thyroid Nodules with Molecular Correlates.

Endocrine pathology - 1 Sept 2024

Alzumaili Bayan A, Fisch Adam S, Faquin William C, Nosé Vania, Randolph Gregory W, Sadow Peter M

Abstract excerpt

RAS p.Q61R is the most prevalent hot-spot mutation in RAS and RAS-like mutated thyroid nodules. A few studies evaluated RAS p.Q61R by immunohistochemistry (RASQ61R-IHC). We performed a retrospective study of an institutional cohort of 150 patients with 217 thyroid lesions tested for RASQ61R-IHC, including clinical, cytologic and molecular data. RASQ61R-IHC was performed on 217 nodules (18% positive, 80% negative,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Membrane Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to Thyroid Neoplasms

Share to Thyroid Nodule

Share to Young Adult

Source

Identifiers

PMID: 39096324
DOI: 10.1007/s12022-024-09821-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of RAS p.Q61R by Immunohistochemistry in Practice: A Clinicopathologic Study of 217 Thyroid Nodules with Molecular Correlates.PMID 39096324Read ↗

NRAS Q61R immunohistochemical staining in thyroid pathology: sensitivity, specificity and utility.Semantic proximity Read ↗

Molecular findings in thyroid tumors: Practical diagnostic, prognostic, and therapeutic insights.Semantic proximity Read ↗

RAS-Mutant Follicular Thyroid Tumors: A Continuous Challenge for Pathologists.Semantic proximity Read ↗

Update on Molecular Diagnostics in Thyroid Pathology: A ReviewSemantic proximity Read ↗

Utilities of RAS Mutations in Preoperative Fine Needle Biopsies for Decision Making for Thyroid Nodule Management: Results from a Single-Center Prospective Cohort.Semantic proximity Read ↗

The histologic outcomes of indeterminate thyroid nodules with rat sarcoma mutations: A case series.Semantic proximity Read ↗

Molecular testing for oncogenic gene mutations in thyroid lesions: a case-control validation study in 413 postsurgical specimens.Semantic proximity Read ↗

Impact of Co-Mutations and Genetic Variations on Malignancy Risk in RAS-Positive Indeterminate Thyroid Nodules: an Institutional Experience.Semantic proximity Read ↗

Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features.Semantic proximity Read ↗

Reappraisal of BRAFK601E-positive thyroid tumors in the NIFTP era.Semantic proximity Read ↗

Does Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP) Have a Unique Molecular Profile?Semantic proximity Read ↗

Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.