Article
Molecular testing for oncogenic gene mutations in thyroid lesions: a case-control validation study in 413 postsurgical specimens.
Human pathology - 1 Jul 2014
Giordano Thomas J, Beaudenon-Huibregtse Sylvie, Shinde Rupali, Langfield Laura, Vinco Michelle, Laosinchai-Wolf Walairat, Labourier Emmanuel
Abstract excerpt
Molecular testing for oncogenic gene alterations provides clinically actionable information essential for the optimal management of follicular cell thyroid cancer. We aimed to establish the distribution and frequency of common oncogenic gene mutations and chromosomal rearrangements in a comprehensive set of benign and malignant thyroid lesions. A case-control study was conducted in 413 surgical cases comprising...
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