Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

6 May 2021

Abstract excerpt

Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely reported in patients after recovery from COVID-19, but some of these patients do not appear to shed infectious virus. We investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the DNA of human cells in culture and that transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33958444
DOI: 10.1073/pnas.2105968118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissuesPMID 33958444Read ↗

ASSESSMENT OF POTENTIAL SARS-CoV-2 VIRUS N GENE INTEGRATION INTO HUMAN GENOME REVEALS NO SIGNIFICANT IMPACT ON RT-qPCR COVID-19 DIAGNOSTIC TESTINGSemantic proximity Read ↗

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencingSemantic proximity Read ↗

Potential Mechanisms for Human Genome Integration of Genetic Code from SARS-CoV-2 mRNA VaccinationSemantic proximity Read ↗

Exogenous Coronavirus Interacts With Endogenous Retrotransposon in Human CellsSemantic proximity Read ↗

SARS-CoV-2-host chimeric RNA-sequencing reads do not necessarily signify virus integration into the host DNASemantic proximity Read ↗

Legal Claims toward SARS-CoV-2 Complementary DNA Integrated into the Human GenomeSemantic proximity Read ↗

Multiple fates of L1 retrotransposition intermediates in cultured human cells.Semantic proximity Read ↗

Characterization of Adeno-Associated Virus Genomes Isolated from Human TissuesSemantic proximity Read ↗

Infectious Molecular Clones of Adeno-Associated Virus Isolated Directly from Human TissuesSemantic proximity Read ↗

Genetic and Biochemical Assays Reveal a Key Role for Replication Restart Proteins in Group II Intron RetrohomingSemantic proximity Read ↗

Characterisation of cytoplasmic DNA complementary to non-retroviral RNA viruses in human cellsSemantic proximity Read ↗

Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.