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Characterisation of cytoplasmic DNA complementary to non-retroviral RNA viruses in human cells

30 May 2014

Abstract excerpt

The synthesis and subsequent genomic integration of DNA that is complementary to the genomes of non-retroviral RNA viruses are rarely observed. However, upon infection of various human cell lines and primary fibroblasts with the vesicular stomatitis virus (VSV), we detected DNA complementary to the VSV RNA. The VSV DNA was detected in the cytoplasm as single-stranded DNA fully complementary to the viral mRNA from...

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PMID: 24875540
DOI: 10.1038/srep05074

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