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Article

BRAF-Mutated Colorectal Cancer: Clinical and Molecular Insights.

International journal of molecular sciences - 28 Oct 2019

Caputo Francesco, Santini Chiara, Bardasi Camilla, Cerma Krisida, Casadei-Gardini Andrea, Spallanzani Andrea, Andrikou Kalliopi, Cascinu Stefano, Gelsomino Fabio

Abstract excerpt

Colorectal cancer (CRC) is one of the leading causes of mortality and morbidity in the world. It is a heterogeneous disease, which can be classified into different subtypes, characterized by specific molecular and morphological alterations. In this context, BRAF mutations are found in about 10% of CRC patients and define a particular subtype, characterized by a dismal prognosis, with a median survival of less...

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Identifiers

PMID: 31661924
DOI: 10.3390/ijms20215369
PMCID: PMC6861966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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