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Article

Case report: recurrent pituitary adenoma has increased load of somatic variants.

BMC endocrine disorders - 29 Jan 2020

Peculis Raitis, Balcere Inga, Radovica-Spalvina Ilze, Konrade Ilze, Caune Olivija, Megnis Kaspars, Rovite Vita, Stukens Janis, Nazarovs Jurijs, Breiksa Austra, Kiecis Aigars, Silamikelis Ivars, Pirags Valdis, Klovins Janis

Abstract excerpt

BACKGROUND: Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurrence. CASE PRESENTATION: The patient was a 69-year-old female with non-functional pituitary macroadenoma with extension into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31996211
DOI: 10.1186/s12902-020-0493-x
PMCID: PMC6988340

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