Article
Celiac disease in pediatric patients according to HLA genetic risk classes: a retrospective observational study.
Italian journal of pediatrics - 5 May 2021
Tolone Carlo, Piccirillo Marisa, Dolce Pasquale, Alfiero Salvatore, Arenella Mattia, Sarnataro Marina, Iardino Patrizia, Pucciarelli Alessia, Strisciuglio Caterina
Abstract excerpt
BACKGROUND: Celiac disease (CD) is an autoimmune enteropathy in which HLA-DQ haplotypes define susceptibility. Our aim was to evaluate if belonging to a certain HLA-DQ class risk could be associated to the clinical, serological and histological presentation of CD. METHODS: We performed a retrospective observational monocentric study including all 300 patients diagnosed with CD, who underwent HLA typing. Clinical,...
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