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Article

Ilex kudingcha C.J. Tseng Mitigates Phenotypic Characteristics of Human Autism Spectrum Disorders in a Drosophila Melanogaster Rugose Mutant.

Neurochemical research - 1 Aug 2021

Pham Hang Thi Nguyet, Tran Hong Nguyen, Le Xoan Thi, Do Ha Thi, Nguyen Tue Trong, Le Nguyen Chien, Yoshida Hideki, Yamaguchi Masamistu, William Folk R, Matsumoto Kinzo

Abstract excerpt

Autism spectrum disorders (ASD) have heterogeneous etiologies involving dysfunction of central nervous systems, for which no effective pan-specific treatments are available. Ilex kudingcha (IK) C.J. Tseng is a nootropic botanical used in Asia for neuroprotection and improvement of cognition. This study establishes that a chemically characterized extract from IK (IKE) mitigates behavioral traits in the Drosophila...

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PMID: 33950474
DOI: 10.1007/s11064-021-03337-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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