Article
Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans
2023-06-05
Abstract excerpt
Liensinine and neferine are the main bisbenzylisoquinoline alkaloids obtained from the seeds of Nelumbo nucifera , which commonly used as edible food and traditional medicine in Asia. It was reported that liensinine and neferine could inhibit the activities of acetylcholinesterase and cross the blood-brain barriers, maybe promising candidates to treat Alzheimer’s disease. Here we employed the APPswe transfected SH...
Topics
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- Adipose Tissue and Metabolism
- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Cholinesterase and Neurodegenerative Diseases
- Genetic Neurodegenerative Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Medicinal Plants and Neuroprotection
- Sirtuins and Resveratrol in Medicine
Identifiers and source
- Literature Corpus work
- 7834bf5e-3098-56e9-82f3-34d030ce20b2
- DOI
- 10.21203/rs.3.rs-3008028/v1
