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Article

MicroRNAs in platelet production and activation

2 Mar 2011

Abstract excerpt

MicroRNAs are small RNA molecules that modulate protein expression by degrading mRNA or repressing translation. They have been shown to play important roles in hematopoiesis, including embryonic stem cell differentiation, erythropoiesis, granulocytopoiesis/monocytopoiesis, lymphopoiesis, and megakaryocytopoiesis. miR-150 and miR-155 play divergent roles in megakaryocytopoiesis, with the former promoting...

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Identifiers

PMID: 21364189
DOI: 10.1182/blood-2011-01-292011

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