Article
DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility.
Cancer medicine - 1 Jun 2021
Li Guyanan, Meng Hua, Bai Yansen, Wei Wei, Feng Yue, Li Mengying, Li Hang, He Meian, Zhang Xiaomin, Wei Sheng, Li Yangkai, Guo Huan
Abstract excerpt
BACKGROUND: Body mass index (BMI) has been reported to be inversely associated with incident risk of non-small cell lung cancer (NSCLC). However, the underlying mechanism is still unclear. This study aimed to investigate the role of DNA methylation in the relationship between BMI and NSCLC. METHODS: We carried out a genome-wide DNA methylation study of BMI in peripheral blood among 2266 Chinese participants by...
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