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Article

Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study.

BMC pulmonary medicine - 16 Jun 2020

Amaral André F S, Imboden Medea, Wielscher Matthias, Rezwan Faisal I, Minelli Cosetta, Garcia-Aymerich Judith, Peralta Gabriela P, Auvinen Juha, Jeong Ayoung, Schaffner Emmanuel, Beckmeyer-Borowko Anna, Holloway John W, Jarvelin Marjo-Riitta, Probst-Hensch Nicole M, Jarvis Deborah L

Abstract excerpt

BACKGROUND: Low lung function has been associated with increased body mass index (BMI). The aim of this study was to investigate whether the effect of BMI on lung function is mediated by DNA methylation. METHODS: We used individual data from 285,495 participants in four population-based cohorts: the European Community Respiratory Health Survey, the Northern Finland Birth Cohort 1966, the Swiss Study on Air...

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Identifiers

PMID: 32546146
DOI: 10.1186/s12890-020-01212-9
PMCID: PMC7298775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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