Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide DNA methylation profiling reveals body mass Index-dependent epigenetic signatures associated with lung cancer susceptibility.

BMC cancer - 28 Jan 2026

Li Zhenzhe, Gao Xiao, Wang Qingwei, Zhao Zhengqin

Abstract excerpt

OBJECTIVE: This study aimed to investigate the association between body mass index (BMI)-related DNA methylation alterations and lung cancer risk. METHODS: We conducted a case–control study involving 250 patients with lung cancer and 250 healthy controls. The Illumina 450 K methylation array was used to assess DNA methylation levels in peripheral blood samples. Multivariate logistic regression analysis was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Body Mass Index
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Obesity

Share to Tumor Suppressor Protein p53

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 41606524
DOI: 10.1186/s12885-025-15536-4
PMCID: PMC12924305

Genes

TP53
ADIPOQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide DNA methylation profiling reveals body mass Index-dependent epigenetic signatures associated with lung cancer susceptibility.PMID 41606524Read ↗

Association Analysis between Body Mass Index and Genomic DNA Methylation across 15 Major Cancer TypesSemantic proximity Read ↗

DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility.Semantic proximity Read ↗

Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactionsSemantic proximity Read ↗

Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco useSemantic proximity Read ↗

Epigenome-Wide Association Study of Chronic Obstructive Pulmonary Disease and Lung Function in KoreansSemantic proximity Read ↗

Metabolic Obesity Phenotypes and Risk of Lung Cancer: A Prospective Cohort Study of 450,482 UK Biobank Participants.Semantic proximity Read ↗

Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral bloodSemantic proximity Read ↗

DNA methylation and body-mass index: a genome-wide analysis.Semantic proximity Read ↗

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetesSemantic proximity Read ↗

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesitySemantic proximity Read ↗

DNA methylation profiling in human lung tissue identifies genes associated with COPDSemantic proximity Read ↗

Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.