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Article

Human Germinal Center Reaction: Assessing T Follicular Helper-B Cells Interaction In Vitro.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Thevenon Emeline, Cornacchione Vanessa, Traggiai Elisabetta, Rucci Francesca

Abstract excerpt

Antibody responses deeply rely on the interaction of antigen-primed B cells and CD4 helper T cells in the context of germinal center reactions, through signals provided by costimulatory molecules and cytokines. B-cell proliferation and differentiation in antibody-secreting plasma cells are processes that critically depend on the helper function of a specific CD4 T-cell subset, known as follicular helper T cells...

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Identifiers

PMID: 33928553
DOI: 10.1007/978-1-0716-1311-5_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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