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Key Disease Mechanisms Linked to Alzheimer’s Disease in the Entorhinal Cortex

10 Apr 2021

Abstract excerpt

Alzheimer's disease (AD) is a chronic, neurodegenerative brain disorder affecting millions of Americans that is expected to increase in incidence with the expanding aging population. Symptomatic AD patients show cognitive decline and often develop neuropsychiatric symptoms due to the accumulation of insoluble proteins that produce plaques and tangles seen in the brain at autopsy. Unexpectedly, some clinically...

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PMID: 33920138
DOI: 10.3390/ijms22083915

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