Article

Therapeutic Targets of Fingolimod (FTY720) in the Brains of Alzheimer's Disease Patients and the Associated Biological Mechanisms: a Network Pharmacology Study

2020-09-23

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe sphingosine-1-phosphate receptor (S1PR) modulator fingolimod (FTY720), which is commonly used as an immunomodulator in multiple sclerosis treatment, was recently reported to be effective in the treatment of Alzheimer’s disease (AD), but its mechanism of action remains elusive. In this study, network pharmacology methods were applied to detect the potential pharmacological...

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Literature Corpus work: 597d749b-c7a3-527a-a435-d2a206f0dae8
DOI: 10.21203/rs.3.rs-80664/v1

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