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Myc-Related Mitochondrial Activity as a Novel Target for Multiple Myeloma

1 Apr 2021

Abstract excerpt

Mitochondria are involved in the development and acquisition of a malignant phenotype in hematological cancers. Recently, their role in the pathogenesis of multiple myeloma (MM) has been suggested to be therapeutically explored. MYC is a master regulator of b-cell malignancies such as multiple myeloma, and its activation is known to deregulate mitochondrial function. We investigated the impact of mitochondrial...

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PMID: 33916196
DOI: 10.3390/cancers13071662

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