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Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

18 Sept 2019

Abstract excerpt

Background Mitochondrial functions are exploited in cancer and provide a validated therapeutic target. However, how this process is regulated has remained mostly elusive and the identification of new pathways that control mitochondrial integrity in cancer is an urgent priority. Methods We studied clinically-annotated patient series of primary and metastatic prostate cancer, representative cases of multiple...

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PMID: 31542392
DOI: 10.1016/j.ebiom.2019.09.017

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