Article
Mitochondrial Changes in Cancer.
Handbook of experimental pharmacology - 1 Jan 2017
Gururaja Rao Shubha
Abstract excerpt
Mitochondrial structural and functional integrity defines the health of a cell by regulating cellular metabolism. Thus, mitochondria play an important role in both cell proliferation and cell death. Cancer cells are metabolically altered compared to normal cells for their ability to survive better and proliferate faster. Resistance to apoptosis is an important characteristic of cancer cells and given the...
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