Article
Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique.
PloS one - 1 Jan 2016
Euler Chad W, Juncosa Barbara, Ryan Patricia A, Deutsch Douglas R, McShan W Michael, Fischetti Vincent A
Abstract excerpt
Streptococcus pyogenes is a human commensal and a bacterial pathogen responsible for a wide variety of human diseases differing in symptoms, severity, and tissue tropism. The completed genome sequences of >37 strains of S. pyogenes, representing diverse disease-causing serotypes, have been published. The greatest genetic variation among these strains is attributed to numerous integrated prophage and prophage-like...
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