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Article

Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study.

Eye (London, England) - 1 Apr 2022

Yu-Wai-Man Patrick, Newman Nancy J, Carelli Valerio, La Morgia Chiara, Biousse Valérie, Bandello Francesco M, Clermont Catherine Vignal, Campillo Lorena Castillo, Leruez Stephanie, Moster Mark L, Cestari Dean M, Foroozan Rod, Sadun Alfredo, Karanjia Rustum, Jurkute Neringa, Blouin Laure, Taiel Magali, Sahel José-Alain

Abstract excerpt

BACKGROUND/OBJECTIVES: REALITY is an international observational retrospective registry of LHON patients evaluating the visual course and outcome in Leber hereditary optic neuropathy (LHON). SUBJECTS/METHODS: Demographics and visual function data were collected from medical charts of LHON patients with visual loss. The study was conducted in 11 study centres in the United States of America and Europe. The...

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Identifiers

PMID: 33911213
DOI: 10.1038/s41433-021-01535-9
PMCID: PMC8956580

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