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Article

Childhood-onset Leber hereditary optic neuropathy.

The British journal of ophthalmology - 1 Nov 2017

Majander Anna, Bowman Richard, Poulton Joanna, Antcliff Richard J, Reddy M Ashwin, Michaelides Michel, Webster Andrew R, Chinnery Patrick F, Votruba Marcela, Moore Anthony T, Yu-Wai-Man Patrick

Abstract excerpt

BACKGROUND: The onset of Leber hereditary optic neuropathy (LHON) is relatively rare in childhood. This study describes the clinical and molecular genetic features observed in this specific LHON subgroup. METHODS: Our retrospective study consisted of a UK paediatric LHON cohort of 27 patients and 69 additional cases identified from a systematic review of the literature. Patients were included if visual loss...

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Identifiers

PMID: 28314831
DOI: 10.1136/bjophthalmol-2016-310072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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