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Article

Leber's Hereditary Optic Neuropathy with Mitochondrial DNA Mutation G11778A: A Systematic Literature Review and Meta-Analysis.

BioMed research international - 1 Jan 2023

Yuan Jiajia, Zhao Jiaxun, Ye Chong, Pang Long, Zhang Xin, Luk Alvin, Du Yangyang, Fan Kai Yoon, Zhang Xiaowen, Li Bin, Chen Changzheng

Abstract excerpt

Background: LHON is a progressive disease with early disease onset and male predominance, usually causing devastating visual loss to patients. These systematic review and meta-analysis are aimed at summarizing epidemiology, disease onset and progression, visual recovery, risk factors, and treatment options of Leber's hereditary optic neuropathy (LHON) with mitochondrial DNA mutation G11778A from current evidence....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 36743514
DOI: 10.1155/2023/1107866
PMCID: PMC9893526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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