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Leber's hereditary optic neuropathy: course of disease in consideration of idebenone treatment and type of mutation.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Apr 2021

Tonagel Felix, Wilhelm Helmut, Richter Paul, Kelbsch Carina

Abstract excerpt

PURPOSE: In September 2015, the first and so far only medication for treatment of Leber's hereditary optic neuropathy (LHON) was approved in the EU. The drug in question is idebenone (©Raxone) and has been given to all newly diagnosed patients of the University Eye Hospital Tuebingen since the approval of the drug. The aim of the study was to find out whether regular administration of the drug led to an...

Topics

DNA, Mitochondrial
Humans
Mutation
Optic Atrophy, Hereditary, Leber
Retrospective Studies
Ubiquinone

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33337510
DOI: 10.1007/s00417-020-05045-4
PMCID: PMC8016777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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