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Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients

7 Apr 2021

Abstract excerpt

Introduction Emerging evidence has suggested that inherited factors are also involved in lung cancer development. However, most studies focused on well-elucidated cancer predisposition genes, the majority of which are tumor suppressor genes. The profile of germline mutations in oncogenic driver genes remains unrevealed, which might also provide potential clinical implications for lung cancer management. Methods...

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PMID: 33898318
DOI: 10.3389/fonc.2021.647598

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