Article
Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort.
Journal of Alzheimer's disease : JAD - 1 Jan 2018
Sellami Leila, Bocchetta Martina, Masellis Mario, Cash David M, Dick Katrina M, van Swieten John, Borroni Barbara, Galimberti Daniela, Tartaglia Maria Carmela, Rowe James B, Graff Caroline, Tagliavini Fabrizio, Frisoni Giovanni, Finger Elizabeth, de Mendonça Alexandre, Sorbi Sandro, Warren Jason D, Rohrer Jonathan D, Laforce Robert
Abstract excerpt
BACKGROUND: The overlap between frontotemporal dementia (FTD) and primary psychiatric disorders has been brought to light by reports of prominent neuropsychiatric symptoms (NPS) in FTD-related genetic mutations, particularly among C9orf72 and GRN carriers. It has been recently demonstrated that early neuroanatomical changes in genetic FTD may be different across the major disease-causing mutations. OBJECTIVE: We...
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