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Article

Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis.

Nature communications - 20 Apr 2021

Ojavee Sven E, Kousathanas Athanasios, Trejo Banos Daniel, Orliac Etienne J, Patxot Marion, Läll Kristi, Mägi Reedik, Fischer Krista, Kutalik Zoltan, Robinson Matthew R

Abstract excerpt

While recent advancements in computation and modelling have improved the analysis of complex traits, our understanding of the genetic basis of the time at symptom onset remains limited. Here, we develop a Bayesian approach (BayesW) that provides probabilistic inference of the genetic architecture of age-at-onset phenotypes in a sampling scheme that facilitates biobank-scale time-to-event analyses. We show in...

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Identifiers

PMID: 33879782
DOI: 10.1038/s41467-021-22538-w
PMCID: PMC8058085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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