Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-inflammatory chemoprevention attenuates the phenotype in a mouse model of esophageal adenocarcinoma.

Carcinogenesis - 19 Aug 2021

Baumeister Theresa, Ingermann Jonas, Marcazzan Sabrina, Fang Hsin-Yu, Oellinger Rupert, Rad Roland, Engleitner Thomas, Kleigrewe Karin, Anand Akanksha, Strangmann Julia, Schmid Roland M, Wang Timothy C, Quante Michael

Abstract excerpt

Barrett's esophagus (BE) is the main known precursor condition of esophageal adenocarcinoma (EAC). BE is defined by the presence of metaplasia above the normal squamous columnar junction and has mainly been attributed to gastroesophageal reflux disease and chronic reflux esophagitis. Thus, the rising incidence of EAC in the Western world is probably mediated by chronic esophageal inflammation, secondary to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Anti-Inflammatory Agents, Non-Steroidal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemoprevention

Share to Diet, High-Fat

Share to Disease Models, Animal

Share to Esophageal Neoplasms

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 33878160
DOI: 10.1093/carcin/bgab032
PMCID: PMC8374059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-inflammatory chemoprevention attenuates the phenotype in a mouse model of esophageal adenocarcinoma.PMID 33878160Read ↗

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarkerSemantic proximity Read ↗

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibitionSemantic proximity Read ↗

Diet-Induced Obesity Exacerbates <i>Helicobacter pylori</i> -Associated Precancerous PhenotypesSemantic proximity Read ↗

Regression of Mouse Prostatic Intraepithelial Neoplasia by Nonsteroidal Anti-inflammatory Drugs in the Transgenic Adenocarcinoma Mouse Prostate ModelSemantic proximity Read ↗

Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.Semantic proximity Read ↗

Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis modelSemantic proximity Read ↗

Beneficial bacteria stimulate host immune cells to counteract dietary and genetic predisposition to mammary cancer in mice.Semantic proximity Read ↗

Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis.Semantic proximity Read ↗

Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression.Semantic proximity Read ↗

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism.Semantic proximity Read ↗

Mouse skin as a model for cancer chemoprevention by nonsteroidal anti-inflammatory drugs.Semantic proximity Read ↗

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.