Article
Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.
Oncogene - 6 May 2004
Zhang Zhongqiu, Wang Yian, Yao Ruisheng, Li Jie, Yan Ying, La Regina Marie, Lemon William L, Grubbs Clinton J, Lubet Ronald A, You Ming
Abstract excerpt
Antitumor B (ATB), also known as Zeng Sheng Ping, is a Chinese herbal mixture composed of six plants. Previously, clinical studies have shown a significant chemopreventive efficacy of ATB against human esophageal and lung cancers. In the present study, A/J mice harboring a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf and treated with benzo[a]pyrene were used to investigate the chemopreventive...
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