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Article

Genetic variants of the EGFR ligand-binding domain and their association with structural alterations in Arab cancer patients.

BMC research notes - 19 Apr 2021

Marzouq Maryam, Nairouz Ali, Ben Khalaf Noureddine, Bourguiba-Hachemi Sonia, Quaddorah Raed, Ashoor Dana, Fathallah M Dahmani

Abstract excerpt

OBJECTIVE: This study aimed to identify novel genetic variants in the CR2 extracellular domain of the epidermal growth factor receptor (EGFR) in healthy individuals and patients with six different types of adenocarcinoma, in Arabian peninsula populations. It also aimed to investigate the effects of these variants on the EGFR structure and their eventual relevance to tumorigenesis. RESULTS: We detected seven new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33874989
DOI: 10.1186/s13104-021-05559-y
PMCID: PMC8054381

Genes

EGFR
CR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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