Article
Benchmarking the Human Leukocyte Antigen Typing Performance of Three Assays and Seven Next-Generation Sequencing-Based Algorithms.
Frontiers in immunology - 1 Jan 2021
Liu Ping, Yao Minya, Gong Yu, Song Yunjie, Chen Yanan, Ye Yizhou, Liu Xiao, Li Fugen, Dong Hua, Meng Rui, Chen Hao, Zheng Aiwen
Abstract excerpt
With the great progress made recently in next generation sequencing (NGS) technology, sequencing accuracy and throughput have increased, while the cost for data has decreased. Various human leukocyte antigen (HLA) typing algorithms and assays have been developed and have begun to be used in clinical practice. In this study, we compared the HLA typing performance of three HLA assays and seven NGS-based HLA...
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