Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics.

doi:10.1192/j.eurpsy.2021.26

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Article

Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics.

European psychiatry : the journal of the Association of European Psychiatrists - 19 Apr 2021

Rampino Antonio, Torretta Silvia, Gelao Barbara, Veneziani Federica, Iacoviello Matteo, Marakhovskaya Aleksandra, Masellis Rita, Andriola Ileana, Sportelli Leonardo, Pergola Giulio, Minelli Alessandra, Magri Chiara, Gennarelli Massimo, Vita Antonio, Beaulieu Jean Martin, Bertolino Alessandro, Blasi Giuseppe

Abstract excerpt

BACKGROUND: Genome-Wide Association Studies (GWASs) have identified several genes associated with Schizophrenia (SCZ) and exponentially increased knowledge on the genetic basis of the disease. In addition, products of GWAS genes interact with neuronal factors coded by genes lacking association, such that this interaction may confer risk for specific phenotypes of this brain disorder. In this regard, fragile X...

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Identifiers

PMID: 33866994
DOI: 10.1192/j.eurpsy.2021.26
PMCID: PMC8260562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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