Article
Neuregulin-1 immunoreactivity in peripheral plasma is associated with rs6982890 polymorphism-mediated psychotic symptoms in schizophrenia.
Brain research bulletin - 15 Oct 2024
Wang Xiujuan, Zhou Jiahui, Ding Shuang, Zhang Jianhong, Liu Yiliang, Liu Ya, Zhao Jingyuan, Shi Han, Liu Qing, Song Meng, Lv Luxian, Li Wenqiang, Yang Yongfeng
Abstract excerpt
OBJECTIVES: Neuregulin 1 (NRG1) is a risk gene for schizophrenia and involved in neurodevelopment and synaptic plasticity. Polymorphisms in NRG1 may affect psychotic symptoms in schizophrenia. This study investigated the effects of the single nucleotide polymorphism (SNP) rs6982890 on peripheral plasma NRG1 immunoreactivity, clinical symptoms and cognitive functions in schizophrenia patients. MATERIAL AND...
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