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Investigation of type I interferon responses in ANCA-associated vasculitis

15 Apr 2021

Abstract excerpt

Type I interferon (IFN) dysregulation is a major contributory factor in the development of several autoimmune diseases, termed type I interferonopathies, and is thought to be the pathogenic link with chronic inflammation in these conditions. Anti-neutrophil cytoplasmic antibody (ANCA)-Associated Vasculitis (AAV) is an autoimmune disease characterised by necrotising inflammation of small blood vessels. The...

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PMID: 33859290
DOI: 10.1038/s41598-021-87760-4

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