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Article

Common variants in CREB1 gene confer risk for bipolar disorder in Han Chinese.

Asian journal of psychiatry - 1 May 2021

Wang Xiaorong, Zhang Guofu, Lu Weihong, Zhang Yi, Fan Weixing, Tang Wei, Zhang Chen

Abstract excerpt

Recently, we have identified involvement of the gene encoding cAMP responsive element-binding 1 (CREB1) in risk of BD in European ancestry. CREB1 has significant genetic diversity between Europeans and Chinese, thereby resulting in diverged CREB1 genetic backgrounds. In this study, we aimed to determine whether CREB1 confers susceptibility to BD and cognitive dysfunction in Han Chinese. We recruited 572 patients...

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PMID: 33848807
DOI: 10.1016/j.ajp.2021.102648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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