Article
Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2021
Yang Soo-Ryum, Chang Jason C, Leduc Charles, Tan Kay See, Dogan Snjezana, Benayed Ryma, Borsu Laetitia, Offin Michael, Drilon Alexander, Travis William D, Arcila Maria E, Ladanyi Marc, Rekhtman Natasha
Abstract excerpt
INTRODUCTION: Pulmonary invasive mucinous adenocarcinomas (IMAs) often present with spatially separate lung lesions. Clonal relationship between such lesions, particularly those involving contralateral lobes, is not well established. Here, we used comparative genomic profiling to address this question. METHODS: Patients with genomic analysis performed on two IMAs located in different lung regions were identified....
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