Genomic characteristics of invasive mucinous adenocarcinoma of the lung with multiple pulmonary sites of involvement.

doi:10.1038/s41379-021-00872-0

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Article

Genomic characteristics of invasive mucinous adenocarcinoma of the lung with multiple pulmonary sites of involvement.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2022

Kim Moonsik, Hwang Jinha, Kim Kyung A, Hwang Sohyun, Lee Hye-Jeong, Jung Ji Ye, Lee Jin Gu, Cha Yoon Jin, Shim Hyo Sup

Abstract excerpt

Invasive mucinous adenocarcinoma (IMA) of the lung frequently presents with diffuse pneumonic-type features or multifocal lesions, which are regarded as a pattern of intrapulmonary metastases. However, the genomics of multifocal IMAs have not been well studied. We performed whole exome sequencing on samples taken from 2 to 5 regions in seven patients with synchronous multifocal IMAs of the lung (24 regions...

Topics

Adenocarcinoma of Lung
Adenocarcinoma, Mucinous
Genomics
Humans
Lung
Lung Neoplasms
Mutation

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Identifiers

PMID: 34290355
DOI: 10.1038/s41379-021-00872-0
PMCID: PMC8786658

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