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Article

Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2009

Girard Nicolas, Ostrovnaya Irina, Lau Christopher, Park Bernard, Ladanyi Marc, Finley David, Deshpande Charuhas, Rusch Valerie, Orlow Irene, Travis William D, Pao William, Begg Colin B

Abstract excerpt

PURPOSE: In cases of multiple non-small cell lung cancer, clinicians must decide whether patients have independent tumors or metastases and tailor treatment accordingly. Decisions are currently made using the Martini and Melamed criteria, which are mostly based on tumor location and histologic type. New genomic tools could improve the ability to assess tumor clonality. EXPERIMENTAL DESIGN: We obtained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19671847
DOI: 10.1158/1078-0432.CCR-09-0594
PMCID: PMC2892178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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