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Article

Using Genomics to Differentiate Multiple Primaries From Metastatic Lung Cancer

16 May 2019

Abstract excerpt

INTRODUCTION: Genomic technologies present a promising mechanism of resolving the clinical dilemma of distinguishing independent primary tumors from intrapulmonary metastases in NSCLC. We evaluated the utility of discordant mapping somatic junctions from chromosomal rearrangements in diagnosing metastatic disease compared to the current standard histologic review. MATERIAL AND METHODS: Mate-pair sequencing was...

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PMID: 31103780
DOI: 10.1016/j.jtho.2019.05.008

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